Charlie calls Sam and Dean and tells them she found the Book of the Dead that could help remove the Mark of Cain. Unfortunately, a man who claims the book belongs to his family shoots her. Meanwhile, Castiel and Metatron take a road trip.
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Sam searches for a magical box built by former Men of Letters that may be able to cure Dean of the Mark of Cain. But the box contains a deadly alarm system that puts the brothers' lives in danger.
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Castiel tries to help Claire Novak find her mom who has been missing for years. He feels guilty for what he did to the Novak family and wants to make amends by reuniting Claire with her mother.
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Sam and Dean investigate a bizarre murder and realize the killer has the same tattoo as those from the Styne family. Meanwhile, Castiel acts as referee when Charlie and Rowena are forced to work together on the Book of the Damned.
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Season 10 ends with the Dean making a shocking decision regarding the Mark of Cain that may change not only his life but Sam's too. Meanwhile, Crowley and Rowena face off, and Castiel gets caught in the middle.
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Sam and Dean go to a small town in Colorado to meet two hunters who have a personal vendetta against monsters that appear once in a generation and cause mysterious disappearances.
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Amara causes a small town to go mad when she places a dark fog upon it; Sam, Dean and the sheriff try to protect the town, but the old remedy fails.
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ABOUT
Twenty-six years ago, Sam Winchester and Dean Winchester lost their mother to a mysterious and demonic supernatural force. Subsequently, their father John raised them to be soldiers. He taught them about the paranormal evil that lives in the dark corners and on the back roads of America ... and he taught them how to kill it.
